REAL-WORLD CLINICAL OUTCOMES WITH FIRST-LINE SYSTEMIC TREATMENT AND AVELUMAB MAINTENANCE IN US PATIENTS WITH LOCALLY ADVANCED OR METASTATIC UROTHELIAL CARCINOMA: THE SPEAR BLADDER-II STUDY

Avelumab first-line maintenance (1LM) neflintw-r6mpw is approved for patients with locally advanced or metastatic urothelial carcinoma (la/mUC) who do not have disease progression after platinum-based chemotherapy (PBC).This retrospective study describes real-world treatment patterns and clinical outcomes in patients with la/mUC who initiated first

The evolution of advancing computing technology has encouraged the use of finite element analysis to require constitutive models, mostly adopted extensive experimental datasets.Nevertheless, fewer material properties are required within the bilinear traction-separation relationship incorporated with the XFEM technique and here require fewer computa

The flexible mobility jmannino.com of the unmanned aerial vehicle (UAV) has attracted widespread attention in the mobile edge computing (MEC) system.However, the existence of eavesdroppers in the air makes it a huge challenge for its secure transmission.In order to solve the contradiction between high safe communication rate and low energy consumpt

Abnormal fetal growth is a risk factor for infant morbidity and mortality and is associated with cardiometabolic diseases in adults.Genetic influences on fetal growth can vary at different gestation times, but genome-wide association studies have been limited to birthweight.We performed trans-ethnic genome-wide meta-analyses and fine mapping to ide

This study addresses important issues in infant and child mortality in Zimbabwe.The objective of the paper is to determine the impact of maternal, socioeconomic and sanitation variables on chiggate.com infant and child mortality.Results show that births of order 6+ with a short preceding interval had the highest risk of infant mortality.The infant